Arcus Biosciences, Inc.
Description
Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. The company's pipeline products include Domvanalimab, an anti-TIGIT antibody, which is in Phase 2 and Phase 3 clinical trial; and AB308, an investigational anti-TIGIT monoclonal antibody, which is in Phase 1b clinical trial to study people with advanced solid and hematologic malignancies. It also develops Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in Phase 2 clinical trial; Quemliclustat, a small-molecule CD73 inhibitor, which is Phase 1b and Phase 2 clinical trial; Zimberelimab, an anti-PD-1 antibody, which is in Phase 2 clinical trial for metastatic cell lung cancer and monotherapy; and AB521, an oral and small-molecule inhibitor of HIF-2a, which is in Phase 1 clinical trial for the treatment of Von Hippel-Lindau disease. In addition, the company's preclinical pipeline products include AB598, a CD39 antibody; and AB801, a small molecule Axl inhibitor. It has a clinical collaboration with AstraZeneca to evaluate domvanalimab in combination with durvalumab in a registrational phase 3 clinical trial in patients with unresectable Stage 3 NSCLC; and BVF Partners L.P. to support the discovery and development of compounds for the treatment of inflammatory diseases. Arcus Biosciences, Inc. was incorporated in 2015 and is headquartered in Hayward, California.
About
Earnings
| Date | Estimate EPS | Actual EPS | Difference | % Surprise |
|---|---|---|---|---|
| Nov 4, 2025 | — | — | — | — |
| Aug 5, 2025 | — | — | — | — |
| May 6, 2025 | — | — | — | — |
| Feb 19, 2025 | -1.20 | — | — | — |
| Nov 7, 2024 | -1.06 | -1.00 | 0.06 | -5.66% |
Earnings estimate
|
Next Quarter
(Mar 2025)
|
Next Year
(Dec 2025)
|
|||
|---|---|---|---|---|
| Number of analysts | — | 2 | — | 7 |
| Average estimate | — | -1.06 | — | -3.66 |
| Low estimate | — | -1.23 | — | -5.43 |
| High estimate | — | -0.89 | — | 0.06 |
| Last year EPS | — | 0.19 | — | -3.16 |
Growth estimates
Analyst Ratings
| Date | Firm | Action | Rating | Price Target |
|---|---|---|---|---|
| Nov 6, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Reiterates | Neutral | Maintains $20 |
| Oct 25, 2024 |
Barclays
Peter Lawson
|
Maintains | Overweight | ▲ Raises $25 → $29 |
| Oct 24, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Reiterates | Neutral | Maintains $20 |
| Oct 21, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Initiates | Neutral | Announces $20 |
| Oct 8, 2024 |
Wells Fargo
Eva Fortea Verdejo
|
Initiates | Overweight | Announces $29 |
| Oct 7, 2024 |
Cantor Fitzgerald
Li Watsek
|
Reiterates | Overweight | — |
| Oct 3, 2024 |
Wedbush
Robert Driscoll
|
Reiterates | Outperform | Maintains $30 |
| Oct 3, 2024 |
Cantor Fitzgerald
Li Watsek
|
Reiterates | Overweight | — |
| Aug 9, 2024 |
Wedbush
Robert Driscoll
|
Reiterates | Outperform | Maintains $30 |
| Aug 9, 2024 |
B of A Securities
Jason Zemansky
|
Maintains | Neutral | ▼ Lowers $24 → $23 |
| Aug 9, 2024 |
Cantor Fitzgerald
Li Watsek
|
Reiterates | Overweight | — |
| Jul 8, 2024 |
Barclays
Peter Lawson
|
Maintains | Overweight | ▼ Lowers $35 → $25 |
| Jul 5, 2024 |
Cantor Fitzgerald
Alethia Young
|
Reiterates | Overweight | — |
| Jun 24, 2024 |
Truist Securities
Asthika Goonewardene
|
Maintains | Buy | ▼ Lowers $50 → $44 |
| Jun 3, 2024 |
Citigroup
Yigal Nochomovitz
|
Maintains | Buy | ▲ Raises $36 → $38 |
| May 13, 2024 |
Morgan Stanley
|
Maintains | Overweight | — |
| May 9, 2024 |
Wedbush
Robert Driscoll
|
Reiterates | Outperform | Maintains $30 |
| Mar 25, 2024 |
Truist Securities
Robyn Karnauskas
|
Reiterates | Buy | Maintains $50 |
| Feb 22, 2024 |
Wedbush
Robert Driscoll
|
Reiterates | Outperform | Maintains $30 |
| Jan 30, 2024 |
Mizuho
Mara Goldstein
|
Maintains | Buy | ▼ Lowers $51 → $42 |
| Jan 30, 2024 |
Wedbush
Robert Driscoll
|
Maintains | Outperform | ▼ Lowers $36 → $30 |
| Jan 17, 2024 |
Wedbush
Robert Driscoll
|
Reiterates | Outperform | Maintains $36 |
| Nov 13, 2023 |
Morgan Stanley
Terence Flynn
|
Maintains | Overweight | ▼ Lowers $38 → $35 |
| Nov 8, 2023 |
Cantor Fitzgerald
Li Watsek
|
Maintains | Overweight | ▼ Lowers $46 → $36 |
| Oct 3, 2023 |
Mizuho
Mara Goldstein
|
Reiterates | Buy | Maintains $51 |
| Sep 12, 2023 |
Cantor Fitzgerald
Alethia Young
|
Reiterates | Overweight | Maintains $46 |
| Sep 7, 2023 |
Cantor Fitzgerald
Alethia Young
|
Reiterates | Overweight | Maintains $46 |
| Sep 6, 2023 |
Truist Securities
Robyn Karnauskas
|
Reiterates | Buy | Maintains $50 |
| Sep 5, 2023 |
B of A Securities
Jason Zemansky
|
Maintains | Neutral | ▲ Raises $21 → $23 |
| Aug 24, 2023 |
Citigroup
Yigal Nochomovitz
|
Maintains | Buy | ▲ Raises $41 → $44 |
Income statement
| 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|
| Fiscal date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total reported revenue | 117.00M | 112.00M | 383.00M | 78.00M | 15.00M |
| Cost of revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating expense | |||||
| Research & development | 340.00M | 288.00M | 257.00M | 159.00M | 78.48M |
| Selling general and admin | 117.00M | 104.00M | 72.00M | 43.00M | 25.23M |
| Other operating expenses | — | — | — | — | — |
| Operating income | -340.00M | -280.00M | 54.00M | -124.00M | -88.71M |
| Non operating interest income | |||||
| Income | 41.00M | 16.00M | 1.00M | 1.00M | 5.20M |
| Expense | 2.00M | 2.00M | — | — | — |
| Other income expense | — | — | — | — | -1.20M |
| Pretax income | -301.00M | -266.00M | 55.00M | -123.00M | -84.71M |
| Tax provision | 6.00M | 1.00M | 2.00M | — | — |
| Net income | -307.00M | -267.00M | 53.00M | -123.00M | -84.71M |
| Basic EPS | -4.15 | -3.71 | 0.76 | -2.24 | -1.93 |
| Diluted EPS | -4.15 | -3.71 | 0.71 | -2.24 | -1.93 |
| Basic average shares | 74.00M | 72.00M | 69.35M | 54.79M | 43.83M |
| Diluted average shares | 74.00M | 72.00M | 69.35M | 54.79M | 43.83M |
| EBITDA | -291.00M | -258.00M | 59.00M | -120.00M | -81.13M |
| Net income from continuing op. | -307.00M | -267.00M | 53.00M | -123.00M | -84.71M |
| Minority interests | — | — | — | — | — |
| Preferred stock dividends | — | — | — | — | — |
Balance sheet
| 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|
| Fiscal date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 1.10B | 1.35B | 1.59B | 772.29M | 203.11M |
| Current assets | |||||
| Cash | — | — | — | — | — |
| Cash equivalents | — | — | — | — | — |
| Cash and cash equivalents | 127.00M | 206.00M | 148.00M | 173.42M | 57.94M |
| Other short term investments | 632.00M | 803.00M | 351.00M | 555.23M | 130.33M |
| Accounts receivable | 38.00M | 39.00M | 745.00M | 1.05M | 132,000 |
| Other receivables | — | — | — | — | — |
| Inventory | — | — | — | — | — |
| Prepaid assets | — | 15.00M | 16.00M | 5.47M | 4.05M |
| Restricted cash | — | — | — | — | — |
| Assets held for sale | — | — | — | — | — |
| Hedging assets | — | — | — | — | — |
| Other current assets | 30.00M | 15.00M | 16.00M | 5.47M | 4.05M |
| Non current assets | |||||
| Properties | 24.00M | 17.00M | 14.00M | 22.68M | 8.17M |
| Land and improvements | — | — | — | — | — |
| Machinery furniture equipment | 3.00M | 3.00M | 2.00M | 1.75M | 1.31M |
| Construction in progress | 1.00M | 4.00M | 2.00M | 2.34M | 238,000 |
| Leases | 54.00M | 34.00M | 32.00M | 11.11M | 10.83M |
| Accumulated depreciation | -31.00M | -23.00M | -18.00M | -14.29M | -11.22M |
| Goodwill | — | — | — | — | — |
| Investment properties | — | — | — | — | — |
| Financial assets | — | — | — | — | — |
| Intangible assets | — | — | — | — | — |
| Investments and advances | 107.00M | 129.00M | 182.00M | 6.44M | — |
| Other non current assets | 106.00M | 114.00M | 116.00M | 6.45M | 1.08M |
| Total liabilities | 633.00M | 688.00M | 750.00M | 269.99M | 39.27M |
| Current liabilities | |||||
| Accounts payable | 17.00M | 20.00M | 10.00M | 15.68M | 4.70M |
| Accrued expenses | 62.00M | 70.00M | 52.00M | 27.85M | 9.52M |
| Short term debt | 11.00M | 3.00M | — | — | — |
| Deferred revenue | 91.00M | 97.00M | 102.00M | 74.57M | 7.00M |
| Tax payable | — | — | 2.00M | — | — |
| Pensions | — | — | — | — | — |
| Other current liabilities | 3.00M | 3.00M | 52,000 | 3.57M | 1.48M |
| Non current liabilities | |||||
| Long term debt | — | — | 116.89M | 15.24M | — |
| Provision for risks and charges | — | — | — | — | — |
| Deferred liabilities | — | — | — | — | — |
| Derivative product liabilities | — | — | — | — | — |
| Other non current liabilities | 142.00M | 140.00M | 122.00M | 543,000 | 806,000 |
| Shareholders equity | |||||
| Common stock | 1.31B | 1.21B | 1.12B | 6,000 | 4,000 |
| Retained earnings | -849.00M | -542.00M | -275.00M | -328.18M | -205.33M |
| Other shareholders equity | — | -7.00M | -1.00M | 44,000 | 64,000 |
| Total shareholders equity | 462.00M | 657.00M | 842.00M | 502.30M | 163.84M |
| Additional paid in capital | — | — | 1.12B | 830.44M | 369.10M |
| Treasury stock | — | — | — | — | — |
| Minority interest | — | — | — | — | — |
Cash flow statement
| 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | |
|---|---|---|---|---|---|---|---|---|
| Operating Activities | ||||||||
| Net Income | -307.00M | -267.00M | 53.00M | -123.00M | -84.71M | -49.59M | -53.08M | -17.97M |
| Depreciation | 8.00M | 6.00M | 4.00M | 3.00M | 3.58M | 3.66M | 2.61M | 1.31M |
| Deferred Taxes | — | — | — | — | — | — | — | — |
| Stock-Based Compensation | 73.00M | 65.00M | 55.00M | 22.00M | 8.98M | 3.87M | 495,000 | 90,000 |
| Other Non-Cash Items | 10.00M | 11.00M | 3.00M | 1.00M | — | -177,000 | -98,000 | 90,000 |
| Accounts Receivable | 15.00M | 704.00M | -17.00M | -1.00M | -49,000 | -58,000 | 380,000 | — |
| Accounts Payable | -1.00M | 8.00M | -5.00M | 9.00M | 1.73M | -69,000 | -267,000 | 3.57M |
| Other Assets & Liabilities | -85.00M | -89.00M | -354.00M | 200.00M | -3.07M | -858,000 | 23.65M | -153,000 |
| Operating Cash Flow | -287.00M | 438.00M | -261.00M | 111.00M | -73.54M | -43.22M | -26.31M | -13.06M |
| Investing Activities | ||||||||
| Capital Expenditures | -24.00M | -6.00M | -26.00M | -3.00M | -1.93M | -3.74M | -5.51M | -4.10M |
| Net Intangibles | — | -3.00M | — | — | — | — | — | — |
| Net Acquisitions | — | — | — | — | — | — | — | -1.00M |
| Purchase of Investments | -788.00M | -1.24B | -719.00M | -740.00M | -247.76M | -261.55M | -96.83M | -33.76M |
| Sale of Investments | 1.01B | 837.00M | 741.00M | 309.00M | 308.89M | 151.86M | 53.27M | — |
| Investing Cash Flow | 194.00M | -410.00M | -4.00M | -434.00M | 59.21M | -113.44M | -49.07M | -39.86M |
| Financing Activities | ||||||||
| Long-Term Debt Issuance | — | — | — | — | — | — | — | — |
| Long-Term Debt Payments | — | — | — | — | — | — | — | — |
| Other Financing Charges | — | 10.00M | 5.00M | — | — | -135,000 | -373,000 | — |
| Financing Cash Flow | 25.00M | 10.00M | 224.99M | 433.95M | -94,000 | 124.98M | 106.50M | 69.82M |
| Other Cash Details | ||||||||
| End Cash Position | 130.00M | 209.00M | 151.00M | 174.00M | 58.14M | 71.27M | 98.43M | 65.16M |
| Income Tax Paid | — | 3.00M | — | — | — | — | — | — |
| Interest Paid | — | — | — | — | — | — | — | — |
| Free Cash Flow | -330.00M | 426.00M | -282.00M | 108.00M | -75.39M | -46.74M | -30.57M | -17.04M |
Top Institutional Holders
| Holder | Date Reported | Shares | Value | % Held |
|---|---|---|---|---|
| iShares Core S&P Smallcap ETF | Nov 30, 2024 | 3,476,736 | 47.18M | 3.80% |
| Fidelity Select Portfolios - Biotechnology | Nov 30, 2024 | 1,879,062 | 25.50M | 2.05% |
| Vanguard Total Stock Market Index Fund | Sep 30, 2024 | 1,616,463 | 21.94M | 1.77% |
| iShares Russell 2000 ETF | Nov 30, 2024 | 1,507,178 | 20.45M | 1.65% |
| SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF | Nov 30, 2024 | 919,193 | 12.47M | 1.00% |
| Vanguard Extended Market Index Fund | Sep 30, 2024 | 849,053 | 11.52M | 0.93% |
| Fidelity Select Portfolios - Pharmaceuticals | Nov 30, 2024 | 760,000 | 10.31M | 0.83% |
| Fidelity Select Portfolios - Health Care | Nov 30, 2024 | 700,000 | 9.50M | 0.76% |
| Vanguard Small-Cap Index Fund | Sep 30, 2024 | 630,221 | 8.55M | 0.69% |
| Fidelity Small Cap Index Fund | Oct 31, 2024 | 554,961 | 7.53M | 0.61% |
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