Arcus Biosciences, Inc.

Description

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. The company's pipeline products include Domvanalimab, an anti-TIGIT antibody, which is in Phase 2 and Phase 3 clinical trial; and AB308, an investigational anti-TIGIT monoclonal antibody, which is in Phase 1b clinical trial to study people with advanced solid and hematologic malignancies. It also develops Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in Phase 2 clinical trial; Quemliclustat, a small-molecule CD73 inhibitor, which is Phase 1b and Phase 2 clinical trial; Zimberelimab, an anti-PD-1 antibody, which is in Phase 2 clinical trial for metastatic cell lung cancer and monotherapy; and AB521, an oral and small-molecule inhibitor of HIF-2a, which is in Phase 1 clinical trial for the treatment of Von Hippel-Lindau disease. In addition, the company's preclinical pipeline products include AB598, a CD39 antibody; and AB801, a small molecule Axl inhibitor. It has a clinical collaboration with AstraZeneca to evaluate domvanalimab in combination with durvalumab in a registrational phase 3 clinical trial in patients with unresectable Stage 3 NSCLC; and BVF Partners L.P. to support the discovery and development of compounds for the treatment of inflammatory diseases. Arcus Biosciences, Inc. was incorporated in 2015 and is headquartered in Hayward, California.

About

CEO
Dr. Terry J. Rosen Ph.D.
Employees
577
Instrument type
Common Stock
Sector
Healthcare
Industry
Biotechnology
MIC code
XNYS
Address
3928 Point Eden Way, Hayward, CA 94545, United States
Phone
510 694 6200
Website
Chart Image
× Enlarged Chart
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Earnings

Date Estimate EPS Actual EPS Difference % Surprise
Nov 4, 2025
Aug 5, 2025
May 6, 2025
Feb 19, 2025 -1.20
Nov 7, 2024 -1.06 -1.00 0.06 -5.66%

Earnings estimate

Next Quarter
(Mar 2025)
Next Year
(Dec 2025)
Number of analysts 2 7
Average estimate -1.06 -3.66
Low estimate -1.23 -5.43
High estimate -0.89 0.06
Last year EPS 0.19 -3.16
[stock_revenue_estimate]

Growth estimates

Current qtr
-11.400%
Next qtr. (Mar 2025)
-671.120%
Current year
23.890%
Next year (Dec 2025)
-15.980%
Next 5 years (per annum)
Past 5 years (per annum)

Analyst Ratings

Date Firm Action Rating Price Target
Nov 6, 2024
HC Wainwright & Co.
Emily Bodnar
Reiterates Neutral Maintains $20
Oct 25, 2024
Barclays
Peter Lawson
Maintains Overweight ▲ Raises $25 → $29
Oct 24, 2024
HC Wainwright & Co.
Emily Bodnar
Reiterates Neutral Maintains $20
Oct 21, 2024
HC Wainwright & Co.
Emily Bodnar
Initiates Neutral Announces $20
Oct 8, 2024
Wells Fargo
Eva Fortea Verdejo
Initiates Overweight Announces $29
Oct 7, 2024
Cantor Fitzgerald
Li Watsek
Reiterates Overweight
Oct 3, 2024
Wedbush
Robert Driscoll
Reiterates Outperform Maintains $30
Oct 3, 2024
Cantor Fitzgerald
Li Watsek
Reiterates Overweight
Aug 9, 2024
Wedbush
Robert Driscoll
Reiterates Outperform Maintains $30
Aug 9, 2024
B of A Securities
Jason Zemansky
Maintains Neutral ▼ Lowers $24 → $23
Aug 9, 2024
Cantor Fitzgerald
Li Watsek
Reiterates Overweight
Jul 8, 2024
Barclays
Peter Lawson
Maintains Overweight ▼ Lowers $35 → $25
Jul 5, 2024
Cantor Fitzgerald
Alethia Young
Reiterates Overweight
Jun 24, 2024
Truist Securities
Asthika Goonewardene
Maintains Buy ▼ Lowers $50 → $44
Jun 3, 2024
Citigroup
Yigal Nochomovitz
Maintains Buy ▲ Raises $36 → $38
May 13, 2024
Morgan Stanley
Maintains Overweight
May 9, 2024
Wedbush
Robert Driscoll
Reiterates Outperform Maintains $30
Mar 25, 2024
Truist Securities
Robyn Karnauskas
Reiterates Buy Maintains $50
Feb 22, 2024
Wedbush
Robert Driscoll
Reiterates Outperform Maintains $30
Jan 30, 2024
Mizuho
Mara Goldstein
Maintains Buy ▼ Lowers $51 → $42
Jan 30, 2024
Wedbush
Robert Driscoll
Maintains Outperform ▼ Lowers $36 → $30
Jan 17, 2024
Wedbush
Robert Driscoll
Reiterates Outperform Maintains $36
Nov 13, 2023
Morgan Stanley
Terence Flynn
Maintains Overweight ▼ Lowers $38 → $35
Nov 8, 2023
Cantor Fitzgerald
Li Watsek
Maintains Overweight ▼ Lowers $46 → $36
Oct 3, 2023
Mizuho
Mara Goldstein
Reiterates Buy Maintains $51
Sep 12, 2023
Cantor Fitzgerald
Alethia Young
Reiterates Overweight Maintains $46
Sep 7, 2023
Cantor Fitzgerald
Alethia Young
Reiterates Overweight Maintains $46
Sep 6, 2023
Truist Securities
Robyn Karnauskas
Reiterates Buy Maintains $50
Sep 5, 2023
B of A Securities
Jason Zemansky
Maintains Neutral ▲ Raises $21 → $23
Aug 24, 2023
Citigroup
Yigal Nochomovitz
Maintains Buy ▲ Raises $41 → $44

Income statement

2023 2022 2021 2020 2019
Fiscal date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Total reported revenue 117.00M 112.00M 383.00M 78.00M 15.00M
Cost of revenue
Gross profit
Operating expense
Research & development 340.00M 288.00M 257.00M 159.00M 78.48M
Selling general and admin 117.00M 104.00M 72.00M 43.00M 25.23M
Other operating expenses
Operating income -340.00M -280.00M 54.00M -124.00M -88.71M
Non operating interest income
Income 41.00M 16.00M 1.00M 1.00M 5.20M
Expense 2.00M 2.00M
Other income expense -1.20M
Pretax income -301.00M -266.00M 55.00M -123.00M -84.71M
Tax provision 6.00M 1.00M 2.00M
Net income -307.00M -267.00M 53.00M -123.00M -84.71M
Basic EPS -4.15 -3.71 0.76 -2.24 -1.93
Diluted EPS -4.15 -3.71 0.71 -2.24 -1.93
Basic average shares 74.00M 72.00M 69.35M 54.79M 43.83M
Diluted average shares 74.00M 72.00M 69.35M 54.79M 43.83M
EBITDA -291.00M -258.00M 59.00M -120.00M -81.13M
Net income from continuing op. -307.00M -267.00M 53.00M -123.00M -84.71M
Minority interests
Preferred stock dividends

Balance sheet

2023 2022 2021 2020 2019
Fiscal date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Total assets 1.10B 1.35B 1.59B 772.29M 203.11M
Current assets
Cash
Cash equivalents
Cash and cash equivalents 127.00M 206.00M 148.00M 173.42M 57.94M
Other short term investments 632.00M 803.00M 351.00M 555.23M 130.33M
Accounts receivable 38.00M 39.00M 745.00M 1.05M 132,000
Other receivables
Inventory
Prepaid assets 15.00M 16.00M 5.47M 4.05M
Restricted cash
Assets held for sale
Hedging assets
Other current assets 30.00M 15.00M 16.00M 5.47M 4.05M
Non current assets
Properties 24.00M 17.00M 14.00M 22.68M 8.17M
Land and improvements
Machinery furniture equipment 3.00M 3.00M 2.00M 1.75M 1.31M
Construction in progress 1.00M 4.00M 2.00M 2.34M 238,000
Leases 54.00M 34.00M 32.00M 11.11M 10.83M
Accumulated depreciation -31.00M -23.00M -18.00M -14.29M -11.22M
Goodwill
Investment properties
Financial assets
Intangible assets
Investments and advances 107.00M 129.00M 182.00M 6.44M
Other non current assets 106.00M 114.00M 116.00M 6.45M 1.08M
Total liabilities 633.00M 688.00M 750.00M 269.99M 39.27M
Current liabilities
Accounts payable 17.00M 20.00M 10.00M 15.68M 4.70M
Accrued expenses 62.00M 70.00M 52.00M 27.85M 9.52M
Short term debt 11.00M 3.00M
Deferred revenue 91.00M 97.00M 102.00M 74.57M 7.00M
Tax payable 2.00M
Pensions
Other current liabilities 3.00M 3.00M 52,000 3.57M 1.48M
Non current liabilities
Long term debt 116.89M 15.24M
Provision for risks and charges
Deferred liabilities
Derivative product liabilities
Other non current liabilities 142.00M 140.00M 122.00M 543,000 806,000
Shareholders equity
Common stock 1.31B 1.21B 1.12B 6,000 4,000
Retained earnings -849.00M -542.00M -275.00M -328.18M -205.33M
Other shareholders equity -7.00M -1.00M 44,000 64,000
Total shareholders equity 462.00M 657.00M 842.00M 502.30M 163.84M
Additional paid in capital 1.12B 830.44M 369.10M
Treasury stock
Minority interest

Cash flow statement

20232022202120202019201820172016
Operating Activities
Net Income-307.00M-267.00M53.00M-123.00M-84.71M-49.59M-53.08M-17.97M
Depreciation8.00M6.00M4.00M3.00M3.58M3.66M2.61M1.31M
Deferred Taxes
Stock-Based Compensation73.00M65.00M55.00M22.00M8.98M3.87M495,00090,000
Other Non-Cash Items10.00M11.00M3.00M1.00M-177,000-98,00090,000
Accounts Receivable15.00M704.00M-17.00M-1.00M-49,000-58,000380,000
Accounts Payable-1.00M8.00M-5.00M9.00M1.73M-69,000-267,0003.57M
Other Assets & Liabilities-85.00M-89.00M-354.00M200.00M-3.07M-858,00023.65M-153,000
Operating Cash Flow-287.00M438.00M-261.00M111.00M-73.54M-43.22M-26.31M-13.06M
Investing Activities
Capital Expenditures-24.00M-6.00M-26.00M-3.00M-1.93M-3.74M-5.51M-4.10M
Net Intangibles-3.00M
Net Acquisitions-1.00M
Purchase of Investments-788.00M-1.24B-719.00M-740.00M-247.76M-261.55M-96.83M-33.76M
Sale of Investments1.01B837.00M741.00M309.00M308.89M151.86M53.27M
Investing Cash Flow194.00M-410.00M-4.00M-434.00M59.21M-113.44M-49.07M-39.86M
Financing Activities
Long-Term Debt Issuance
Long-Term Debt Payments
Other Financing Charges10.00M5.00M-135,000-373,000
Financing Cash Flow25.00M10.00M224.99M433.95M-94,000124.98M106.50M69.82M
Other Cash Details
End Cash Position130.00M209.00M151.00M174.00M58.14M71.27M98.43M65.16M
Income Tax Paid3.00M
Interest Paid
Free Cash Flow-330.00M426.00M-282.00M108.00M-75.39M-46.74M-30.57M-17.04M

Top Institutional Holders

Holder Date Reported Shares Value % Held
iShares Core S&P Smallcap ETF Nov 30, 2024 3,476,736 47.18M 3.80%
Fidelity Select Portfolios - Biotechnology Nov 30, 2024 1,879,062 25.50M 2.05%
Vanguard Total Stock Market Index Fund Sep 30, 2024 1,616,463 21.94M 1.77%
iShares Russell 2000 ETF Nov 30, 2024 1,507,178 20.45M 1.65%
SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF Nov 30, 2024 919,193 12.47M 1.00%
Vanguard Extended Market Index Fund Sep 30, 2024 849,053 11.52M 0.93%
Fidelity Select Portfolios - Pharmaceuticals Nov 30, 2024 760,000 10.31M 0.83%
Fidelity Select Portfolios - Health Care Nov 30, 2024 700,000 9.50M 0.76%
Vanguard Small-Cap Index Fund Sep 30, 2024 630,221 8.55M 0.69%
Fidelity Small Cap Index Fund Oct 31, 2024 554,961 7.53M 0.61%
Arcus Biosciences Announces New Employment Inducement Grants Article
Arcus Biosciences Announces New Employment Inducement Grants
HAYWARD, Calif.--(BUSINESS WIRE)--Arcus Biosciences, Inc. (NYSE:RCUS), a clinical-stage, global biopharmaceutical company focused on developing differentiated molecules and combination therapies for people with cancer, today announced that the Compensation Committee of the Company's Board of Directors granted four new employees options to purchase a total of 31,800 shares of the Company's common stock at an exercise price per share of $13.33, which was the closing price on January 23, 2024, and.
Business Wire Neutral
Jan 24, 2025
Arcus Biosciences Appoints Richard Markus, M.D., Ph.D. as Chief Medical Officer Article
Arcus Biosciences Appoints Richard Markus, M.D., Ph.D. as Chief Medical Officer
HAYWARD, Calif.--(BUSINESS WIRE)--Arcus Biosciences, Inc. (NYSE:RCUS), a clinical-stage, global biopharmaceutical company focused on developing differentiated molecules and combination therapies for people with cancer, today announced that Richard Markus, M.D., Ph.D., has been appointed chief medical officer (CMO) effective January 31, 2025. Dr. Markus replaces Dimitry Nuyten, M.D., Ph.D., who will be leaving the company at the end of January to pursue other opportunities. Dr. Markus's responsi.
Business Wire Neutral
Jan 21, 2025
Arcus Biosciences: Many Important Oncology Catalysts Coming Up In 2025 Article
Arcus Biosciences: Many Important Oncology Catalysts Coming Up In 2025
Arcus Biosciences has interesting combination therapies that target several diseases like NSCLC, RCC, GI, and pancreatic cancers. The company has a few ongoing Phase 3 trials, some of which will report important updates in 2025. One of Domvanalimab's combinations showed that it can help overall survival by a whopping 36% in NSCLC. It also had lower discontinuation rates than chemotherapy.
Seeking Alpha Positive
Jan 15, 2025
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