Mirum Pharmaceuticals, Inc.
Description
Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under Phase 3 development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases. The company was incorporated in 2018 and is headquartered in Foster City, California.
About
Earnings
Date | Estimate EPS | Actual EPS | Difference | % Surprise |
---|---|---|---|---|
Nov 10, 2025 | — | — | — | — |
Aug 6, 2025 | — | — | — | — |
May 6, 2025 | — | — | — | — |
Feb 26, 2025 | — | — | — | — |
Nov 12, 2024 | -0.45 | -0.30 | 0.15 | -33.33% |
Earnings estimate
Next Quarter
(Mar 2025)
|
Next Year
(Dec 2025)
|
|||
---|---|---|---|---|
Number of analysts | — | 5 | — | 7 |
Average estimate | — | -0.26 | — | -0.52 |
Low estimate | — | -0.46 | — | -1.55 |
High estimate | — | -0.08 | — | 1.00 |
Last year EPS | — | -0.54 | — | -1.42 |
Growth estimates
Analyst Ratings
Date | Firm | Action | Rating | Price Target |
---|---|---|---|---|
Nov 13, 2024 |
Citigroup
David Lebowitz
|
Maintains | Buy | ▲ Raises $65 → $68 |
Nov 13, 2024 |
Baird
Brian Skorney
|
Maintains | Outperform | ▲ Raises $44 → $50 |
Nov 13, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $66 |
Oct 17, 2024 |
Leerink Partners
Mani Foroohar
|
Maintains | Outperform | ▲ Raises $47 → $49 |
Oct 11, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $66 |
Aug 8, 2024 |
Evercore ISI Group
Gavin Clark-Gartner
|
Maintains | Outperform | ▲ Raises $62 → $66 |
Aug 8, 2024 |
Cantor Fitzgerald
Josh Schimmer
|
Maintains | Overweight | ▲ Raises $50 → $60 |
Aug 8, 2024 |
Baird
Brian Skorney
|
Maintains | Outperform | ▲ Raises $39 → $44 |
Jul 26, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $66 |
Jul 8, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $66 |
Jun 28, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $66 |
Jun 20, 2024 |
Stifel
Dae Gon Ha
|
Maintains | Buy | ▲ Raises $48 → $66 |
Jun 18, 2024 |
Morgan Stanley
Michael Ulz
|
Maintains | Overweight | ▲ Raises $53 → $57 |
Jun 18, 2024 |
JMP Securities
Jonathan Wolleben
|
Maintains | Market Outperform | ▲ Raises $66 → $68 |
Jun 18, 2024 |
JP Morgan
Jessica Fye
|
Maintains | Overweight | ▲ Raises $31 → $39 |
Jun 18, 2024 |
Citigroup
David Lebowitz
|
Maintains | Buy | ▲ Raises $38 → $64 |
Jun 17, 2024 |
HC Wainwright & Co.
Ed Arce
|
Maintains | Buy | ▲ Raises $58 → $66 |
Jun 17, 2024 |
Baird
Brian Skorney
|
Maintains | Outperform | ▲ Raises $34 → $39 |
Jun 17, 2024 |
Stifel
Dae Gon Ha
|
Reiterates | Buy | Maintains $48 |
Jun 7, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $58 |
Jun 3, 2024 |
HC Wainwright & Co.
|
Reiterates | Buy | Maintains $58 |
May 10, 2024 |
Morgan Stanley
Michael Ulz
|
Maintains | Overweight | ▼ Lowers $57 → $53 |
May 9, 2024 |
Citigroup
David Lebovitz
|
Maintains | Buy | ▲ Raises $37 → $38 |
May 9, 2024 |
JMP Securities
Jonathan Wolleben
|
Maintains | Market Outperform | ▼ Lowers $72 → $66 |
May 9, 2024 |
Cantor Fitzgerald
Josh Schimmer
|
Reiterates | Overweight | Maintains $40 |
May 9, 2024 |
HC Wainwright & Co.
Ed Arce
|
Reiterates | Buy | Maintains $58 |
Apr 17, 2024 |
Stifel
Dae Gon Ha
|
Initiates | Buy | Announces $48 |
Apr 2, 2024 |
HC Wainwright & Co.
Ed Arce
|
Maintains | Buy | Maintains $58 |
Mar 18, 2024 |
Leerink Partners
Mani Foroohar
|
Maintains | Outperform | ▼ Lowers $44 → $43 |
Mar 14, 2024 |
JMP Securities
Jonathan Wolleben
|
Maintains | Outperform | ▲ Raises $69 → $72 |
Income statement
2023 | 2022 | 2021 | 2020 | 2019 | |
---|---|---|---|---|---|
Fiscal date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
Total reported revenue | 186.37M | 77.06M | 19.14M | — | — |
Cost of revenue | 47.04M | 12.37M | 1.90M | — | — |
Gross profit | 139.34M | 64.69M | 17.24M | — | — |
Operating expense | |||||
Research & development | 102.61M | 106.84M | 131.43M | 81.61M | 42.99M |
Selling general and admin | 145.88M | 89.07M | 59.22M | 22.69M | 11.75M |
Other operating expenses | — | — | — | — | — |
Operating income | -109.15M | -131.22M | -173.41M | -104.30M | -54.74M |
Non operating interest income | |||||
Income | 13.74M | 3.86M | 366,000 | 1.56M | 2.23M |
Expense | 15.11M | 15.98M | 17.59M | 335,000 | — |
Other income expense | -51.90M | 1.27M | 106.69M | -192,000 | -21,000 |
Pretax income | -162.42M | -142.07M | -83.95M | -103.26M | -52.53M |
Tax provision | 991,000 | -6.41M | 37,000 | 6,000 | 21,000 |
Net income | -163.42M | -135.67M | -83.99M | -103.27M | -52.55M |
Basic EPS | -4.00 | -4.01 | -2.77 | -4.09 | -4.58 |
Diluted EPS | -4.00 | -4.02 | -2.77 | -4.09 | -4.58 |
Basic average shares | 40.89M | 33.84M | 30.32M | 25.25M | 11.49M |
Diluted average shares | 40.89M | 33.84M | 30.32M | 25.25M | 11.49M |
EBITDA | -87.41M | -123.76M | -65.03M | -102.31M | -52.21M |
Net income from continuing op. | -163.42M | -135.67M | -83.99M | -103.27M | -52.55M |
Minority interests | — | — | — | — | — |
Preferred stock dividends | — | — | — | — | — |
Balance sheet
2023 | 2022 | 2021 | 2020 | 2019 | |
---|---|---|---|---|---|
Fiscal date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
Total assets | 646.62M | 352.91M | 294.65M | 240.86M | 146.71M |
Current assets | |||||
Cash | — | — | — | — | — |
Cash equivalents | — | — | — | — | — |
Cash and cash equivalents | 286.33M | 28.00M | 31.34M | 142.09M | 11.97M |
Other short term investments | — | 123.72M | 125.20M | 89.73M | 104.69M |
Accounts receivable | 67.97M | 23.99M | 3.27M | — | — |
Other receivables | — | — | — | — | — |
Inventory | 22.31M | 5.57M | 1.51M | — | — |
Prepaid assets | — | — | 5.27M | 4.53M | 2.70M |
Restricted cash | — | — | — | — | — |
Assets held for sale | — | — | — | — | — |
Hedging assets | — | — | — | — | — |
Other current assets | 10.94M | 8.95M | 5.27M | 4.53M | 2.70M |
Non current assets | |||||
Properties | 706,000 | 914,000 | 981,000 | 3.24M | 3.73M |
Land and improvements | — | — | — | — | — |
Machinery furniture equipment | — | — | — | — | — |
Construction in progress | — | — | — | — | — |
Leases | — | — | — | — | — |
Accumulated depreciation | — | — | — | — | — |
Goodwill | 252.93M | 58.95M | 18.74M | — | — |
Investment properties | — | — | — | — | — |
Financial assets | — | — | — | — | — |
Intangible assets | 252.93M | 58.95M | 18.74M | — | — |
Investments and advances | — | — | 4.98M | — | 23.29M |
Other non current assets | 4.17M | 101.38M | 101.79M | 1.27M | 324,000 |
Total liabilities | 397.95M | 210.87M | 174.44M | 68.77M | 16.36M |
Current liabilities | |||||
Accounts payable | 7.42M | 8.69M | 9.17M | 3.15M | 3.35M |
Accrued expenses | 50.89M | 36.90M | 20.13M | 8.61M | 7.11M |
Short term debt | 1.10M | 931,000 | 711,000 | 636,000 | 397,000 |
Deferred revenue | — | — | — | — | — |
Tax payable | — | — | — | — | — |
Pensions | 20.94M | 14.66M | 9.99M | 4.80M | 2.22M |
Other current liabilities | — | 1.09M | 2.00M | 1.26M | — |
Non current liabilities | |||||
Long term debt | 307.04M | 1.26M | 1.90M | 2.63M | 3.25M |
Provision for risks and charges | — | — | — | — | — |
Deferred liabilities | — | — | — | — | — |
Derivative product liabilities | — | — | — | — | — |
Other non current liabilities | 3.85M | 4.53M | 17,000 | 29,000 | 36,000 |
Shareholders equity | |||||
Common stock | 5,000 | 4,000 | 3,000 | 3,000 | 2,000 |
Retained earnings | -556.24M | -392.82M | -257.16M | -173.17M | -69.90M |
Other shareholders equity | 1.64M | -217,000 | -35,000 | 83,000 | 129,000 |
Total shareholders equity | 248.67M | 142.04M | 120.21M | 172.10M | 130.35M |
Additional paid in capital | 803.26M | 535.07M | 377.40M | 345.18M | 200.12M |
Treasury stock | — | — | — | — | — |
Minority interest | — | — | — | — | — |
Cash flow statement
2023 | 2022 | 2021 | 2020 | 2019 | |
---|---|---|---|---|---|
Operating Activities | |||||
Net Income | -163.42M | -135.67M | -83.99M | -103.27M | -52.55M |
Depreciation | 10.83M | 3.24M | 595,000 | 623,000 | 324,000 |
Deferred Taxes | — | -6.58M | — | — | — |
Stock-Based Compensation | 35.02M | 27.01M | 23.09M | 12.55M | 6.07M |
Other Non-Cash Items | 56.54M | 15.52M | -90.03M | 335,000 | — |
Accounts Receivable | -43.97M | -20.73M | — | — | — |
Accounts Payable | 30.78M | 7.64M | 22.66M | 3.68M | 10.06M |
Other Assets & Liabilities | -5.84M | -4.29M | -1.66M | -1.15M | -277,000 |
Operating Cash Flow | -80.06M | -113.85M | -129.34M | -87.23M | -36.38M |
Investing Activities | |||||
Capital Expenditures | -109,000 | -278,000 | -24,000 | -225,000 | -281,000 |
Net Intangibles | -20.00M | — | -19.00M | — | — |
Net Acquisitions | -212.76M | — | — | — | — |
Purchase of Investments | -27.33M | -132.32M | -198.03M | -74.56M | -152.00M |
Sale of Investments | 153.00M | 140.30M | 157.60M | 112.66M | 24.50M |
Investing Cash Flow | -87.20M | 7.70M | 67.55M | 37.87M | -127.78M |
Financing Activities | |||||
Long-Term Debt Issuance | 305.30M | — | — | — | — |
Long-Term Debt Payments | — | — | — | — | — |
Other Financing Charges | -195.86M | -5.55M | 64.45M | 49.42M | — |
Financing Cash Flow | 326.13M | 101.82M | 71.37M | 181.29M | 127.18M |
Other Cash Details | |||||
End Cash Position | 286.33M | 128.00M | 131.34M | 142.09M | 11.97M |
Income Tax Paid | 125,000 | — | — | 11,000 | 21,000 |
Interest Paid | 6.82M | — | — | — | — |
Free Cash Flow | -91.05M | -120.41M | -151.78M | -89.30M | -39.64M |
Top Institutional Holders
Holder | Date Reported | Shares | Value | % Held |
---|---|---|---|---|
Mutual Fund Ser Tr-Eventide Gilead Fund | Sep 30, 2024 | 1,771,533 | 92.62M | 3.69% |
Mutual Fund Ser Tr-Eventide Healthcare & Life Sciences Fund | Sep 30, 2024 | 1,665,883 | 87.09M | 3.47% |
Vanguard Total Stock Market Index Fund | Sep 30, 2024 | 1,407,511 | 73.58M | 2.93% |
iShares Russell 2000 ETF | Nov 30, 2024 | 1,098,016 | 57.40M | 2.29% |
SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF | Nov 30, 2024 | 932,953 | 48.77M | 1.94% |
Janus Henderson Global Life Sciences Fund | Sep 30, 2024 | 828,132 | 43.29M | 1.73% |
Price (T.Rowe) New Horizons Fund | Sep 30, 2024 | 768,367 | 40.17M | 1.60% |
Janus Henderson Triton Fund | Sep 30, 2024 | 712,389 | 37.24M | 1.48% |
Legg Mason Clearbridge Small Cap Growth Fd | Oct 31, 2024 | 648,193 | 33.89M | 1.35% |
Vanguard Extended Market Index Fund | Sep 30, 2024 | 588,847 | 30.78M | 1.23% |