AnaptysBio, Inc.

Description

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics. Its products include Rosnilimab, an IgG1 antibody that targets PD-1+ T cells, resulting in their agonism or depletion, broadly impacting pathogenic drivers of autoimmune and inflammatory diseases; and ANB032, a non-depleting antibody that binds to the BTLA checkpoint receptor and inhibits activated T cell proliferation; ANB033, a novel anti-CD122 antagonist antibody that targets the shared common beta subunit of the receptors for IL-15 and IL-2; ANB101, a BDCA2 modulator antibody that specifically targets plasmacytoid dendritic cells (pDCs); and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

About

CEO
Mr. Daniel R. Faga
Employees
117
Instrument type
Common Stock
Sector
Healthcare
Industry
Biotechnology
MIC code
XNGS
Address
10770 Wateridge Circle, San Diego, CA 92121-5801, United States
Phone
858 362 6295
Website
Chart Image
× Enlarged Chart
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Earnings

Date Estimate EPS Actual EPS Difference % Surprise
Nov 3, 2025
Aug 4, 2025
May 7, 2025
Mar 10, 2025 -1.55
Nov 6, 2024 -1.65 -1.14 0.51 -30.91%

Earnings estimate

Next Quarter
(Mar 2025)
Next Year
(Dec 2025)
Number of analysts 6 8
Average estimate -1.52 -5.87
Low estimate -1.77 -7.36
High estimate -1.08 -4.50
Last year EPS -1.64 -6.18
[stock_revenue_estimate]

Growth estimates

Current qtr
-7.220%
Next qtr. (Mar 2025)
7.320%
Current year
-1.660%
Next year (Dec 2025)
4.970%
Next 5 years (per annum)
Past 5 years (per annum)

Analyst Ratings

Date Firm Action Rating Price Target
Feb 4, 2025
HC Wainwright & Co.
Emily Bodnar
Reiterates Neutral Maintains $19
Feb 4, 2025
Wolfe Research
Andy Chen
Initiates Outperform
Dec 19, 2024
JP Morgan
Anupam Rama
Maintains Overweight ▼ Lowers $66 → $36
Dec 18, 2024
Truist Securities
John Lee
Maintains Hold ▼ Lowers $30 → $20
Dec 12, 2024
Guggenheim
Yatin Suneja
Maintains Buy ▼ Lowers $90 → $36
Dec 12, 2024
Wells Fargo
Derek Archila
Maintains Overweight ▼ Lowers $56 → $40
Dec 11, 2024
HC Wainwright & Co.
Emily Bodnar
Downgrade Neutral
Dec 2, 2024
BTIG
Julian Harrison
Downgrade Neutral
Nov 12, 2024
JP Morgan
Anupam Rama
Maintains Overweight ▼ Lowers $75 → $66
Nov 6, 2024
HC Wainwright & Co.
Emily Bodnar
Maintains Buy ▼ Lowers $55 → $52
Oct 31, 2024
HC Wainwright & Co.
Emily Bodnar
Reiterates Buy Maintains $55
Oct 30, 2024
UBS
Eliana Merle
Maintains Neutral ▲ Raises $23 → $33
Oct 21, 2024
Guggenheim
Yatin Suneja
Maintains Buy ▲ Raises $75 → $90
Sep 26, 2024
Wedbush
David Nierengarten
Reiterates Outperform Maintains $42
Aug 15, 2024
Truist Securities
John Lee
Maintains Hold ▲ Raises $20 → $30
Aug 14, 2024
HC Wainwright & Co.
Emily Bodnar
Reiterates Buy Maintains $55
Aug 7, 2024
JP Morgan
Anupam Rama
Maintains Overweight ▲ Raises $69 → $75
Aug 6, 2024
HC Wainwright & Co.
Emily Bodnar
Reiterates Buy Maintains $55
Jul 22, 2024
HC Wainwright & Co.
Emily Bodnar
Initiates Buy Announces $55
Jul 19, 2024
JP Morgan
Anupam Rama
Upgrade Overweight ▲ Raises $29 → $69
May 10, 2024
Wedbush
David Nierengarten
Reiterates Outperform Maintains $34
Apr 16, 2024
Leerink Partners
David Risinger
Initiates Outperform Announces $47
Apr 11, 2024
Wells Fargo
Derek Archila
Initiates Overweight Announces $56
Apr 1, 2024
JP Morgan
Anupam Rama
Maintains Neutral ▼ Lowers $30 → $28
Mar 12, 2024
Wedbush
David Nierengarten
Upgrade Outperform
Feb 26, 2024
BTIG
Julian Harrison
Initiates Buy Announces $55
Feb 21, 2024
Stifel
Alex Schwartz
Initiates Buy Announces $50
Feb 16, 2024
Piper Sandler
Yasmeen Rahimi
Initiates Overweight Announces $80
Nov 29, 2023
Wedbush
David Nierengarten
Reiterates Neutral Maintains $20
Nov 3, 2023
Wedbush
David Nierengarten
Maintains Neutral ▲ Raises $18 → $20

Income statement

2023 2022 2021 2020 2019
Fiscal date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Total reported revenue 17.16M 10.29M 63.18M 75.00M 8.00M
Cost of revenue
Gross profit
Operating expense
Research & development 132.28M 88.80M 98.50M 80.03M 99.34M
Selling general and admin 41.95M 36.64M 21.49M 18.85M 16.09M
Other operating expenses
Operating income -157.07M -115.15M -56.81M -23.88M -107.43M
Non operating interest income
Income 18.87M 7.55M 431,000 3.96M 10.98M
Expense 18.08M 21.11M 1.45M 1.04M
Other income expense -7.34M 12,000 37,000 -11,000 1,000
Pretax income -163.62M -128.70M -57.80M -19.93M -97.49M
Tax provision -4,000 24,000 -152,000
Net income -163.62M -128.72M -57.80M -19.93M -97.34M
Basic EPS -6.08 -4.57 -2.11 -0.73 -3.60
Diluted EPS -6.08 -4.57 -2.11 -0.73 -3.60
Basic average shares 26.92M 28.17M 27.43M 27.30M 27.06M
Diluted average shares 26.92M 28.17M 27.43M 27.30M 27.06M
EBITDA -135.83M -105.26M -54.26M -18.31M -95.04M
Net income from continuing op. -163.62M -128.72M -57.80M -19.93M -97.34M
Minority interests
Preferred stock dividends

Balance sheet

2023 2022 2021 2020 2019
Fiscal date 2023-12-31 2022-12-31 2021-12-31 2020-12-31 2019-12-31
Total assets 452.39M 610.38M 643.07M 416.55M 435.20M
Current assets
Cash
Cash equivalents
Cash and cash equivalents 35.97M 71.31M 495.73M 250.46M 171.02M
Other short term investments 354.94M 369.93M 52.37M 143.20M 203.21M
Accounts receivable 6.85M 1.42M 876,000
Other receivables
Inventory
Prepaid assets 4.90M 2.91M 3.51M
Restricted cash
Assets held for sale
Hedging assets
Other current assets 9.08M 4.55M 4.90M 2.91M 3.51M
Non current assets
Properties 22.65M 23.77M 25.24M 5.57M 4.91M
Land and improvements
Machinery furniture equipment 1.64M 1.59M 1.32M 976,000 811,000
Construction in progress
Leases 203,000 203,000 203,000 527,000 575,000
Accumulated depreciation -6.22M -5.58M -4.92M -4.95M -4.68M
Goodwill
Investment properties
Financial assets
Intangible assets
Investments and advances 27.03M 142.94M 67.10M 17.55M 54.31M
Other non current assets 256,000 256,000 256,000 318,000 1.54M
Total liabilities 364.29M 348.28M 286.64M 19.82M 30.19M
Current liabilities
Accounts payable 4.70M 2.78M 1.74M 4.22M 16.24M
Accrued expenses 23.77M 16.25M 8.68M 11.57M 8.90M
Short term debt 1.78M 1.64M 1.51M 342,000 2.25M
Deferred revenue
Tax payable
Pensions 7.20M 5.38M 4.18M 3.69M 2.15M
Other current liabilities 871,000
Non current liabilities
Long term debt 16.04M 17.81M 19.45M 654,000
Provision for risks and charges
Deferred liabilities
Derivative product liabilities
Other non current liabilities 310.81M 304.41M 251.09M 654,000
Shareholders equity
Common stock 27,000 29,000 28,000 27,000 27,000
Retained earnings -614.10M -450.48M -321.75M -263.96M -244.03M
Other shareholders equity -797,000 -5.25M -422,000 -4,000 338,000
Total shareholders equity 88.10M 262.10M 356.43M 396.73M 405.01M
Additional paid in capital 702.97M 717.80M 678.58M 660.67M 648.67M
Treasury stock
Minority interest

Cash flow statement

20232022202120202019201820172016201520142013
Operating Activities
Net Income-163.62M-128.72M-57.80M-19.93M-97.34M-61.66M-30.07M-4.26M-5.41M3.53M-5.55M
Depreciation2.38M2.34M2.09M1.62M1.41M315,000183,000233,000274,000308,000580,000
Deferred Taxes
Stock-Based Compensation33.21M27.36M15.35M11.50M12.41M9.96M4.38M1.16M604,000160,000151,000
Other Non-Cash Items18.08M21.11M1.45M676,000646,000619,000105,000110,0001.27M886,000
Accounts Receivable-5.43M-543,000-876,000174,0001.43M3.74M-4.12M229,000-1.46M268,000
Accounts Payable10.94M9.70M-4.74M-7.69M13.20M7.08M2.22M1.25M1.95M482,000-255,000
Other Assets & Liabilities-1.64M-1.51M-72,000-1.18M-999,000139,000-3.08M-9.08M10.76M-1.39M
Operating Cash Flow-106.09M-70.27M-44.60M-15.69M-70.46M-42.09M-18.93M-8.71M-11.32M15.06M-5.31M
Investing Activities
Capital Expenditures-807,000-358,000-1.35M-569,000-805,000-1.06M-290,000-50,000-238,000-140,000-37,000
Net Intangibles
Net Acquisitions
Purchase of Investments-303.92M-802.50M-118.66M-194.93M-251.82M-347.54M-290.91M
Sale of Investments449.48M408.02M158.85M289.97M384.05M206.15M48.14M
Investing Cash Flow144.75M-394.85M38.84M94.48M131.43M-142.45M-243.06M-50,000-238,000-140,000-37,000
Financing Activities
Long-Term Debt Issuance10.00M5.00M
Long-Term Debt Payments-1.38M-7.50M-6.88M
Other Financing Charges-11.77M32.19M249.75M-182,000-1.60M-1.40M-1.45M-85,000
Financing Cash Flow-59.30M44.02M252.30M-2.25M-11.99M213.54M290.94M8.60M39.24M4.92M1.96M
Other Cash Details
End Cash Position35.97M71.31M495.73M250.52M171.08M113.66M81.25M51.29M51.74M22.19M2.81M
Income Tax Paid
Interest Paid4,000424,0001.04M1.09M354,000326,0008,000
Free Cash Flow-121.61M-73.95M-47.29M-14.73M-70.32M-49.57M-19.73M-9.08M-9.93M14.46M-5.83M
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Anaptys to Present at the Guggenheim SMID Cap Biotech Conference Article
Anaptys to Present at the Guggenheim SMID Cap Biotech Conference
SAN DIEGO, Feb. 03, 2025 (GLOBE NEWSWIRE) -- AnaptysBio, Inc. (Nasdaq: ANAB), a clinical-stage biotechnology company focused on delivering innovative immunology therapeutics, today announced that Daniel Faga, president and chief executive officer of Anaptys, will present at the Guggenheim SMID Cap Biotech Conference on Wednesday, Feb. 5, 2025 at 1:00pm ET / 10:00am PT.
GlobeNewsWire Neutral
Feb 3, 2025
Vanda Pharmaceuticals and Anaptys Announce Exclusive Global License Agreement for Vanda to Develop and Commercialize Imsidolimab, an IL-36R Antagonist Article
Vanda Pharmaceuticals and Anaptys Announce Exclusive Global License Agreement for Vanda to Develop and Commercialize Imsidolimab, an IL-36R Antagonist
WASHINGTON and SAN DIEGO, Feb. 03, 2025 (GLOBE NEWSWIRE) -- Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA) and AnaptysBio, Inc. (Anaptys) (Nasdaq: ANAB) today announced an exclusive, global license agreement for the development and commercialization of imsidolimab (IL-36R antagonist mAb), which has successfully completed two registration-enabling global Phase 3 trials, GEMINI-1 and GEMINI-2, evaluating the safety and efficacy of imsidolimab in patients with Generalized Pustular Psoriasis (GPP).
GlobeNewsWire Neutral
Feb 3, 2025
Are Medical Stocks Lagging AnaptysBio (ANAB) This Year? Article
Are Medical Stocks Lagging AnaptysBio (ANAB) This Year?
Here is how AnaptysBio, Inc. (ANAB) and Inspire Medical Systems (INSP) have performed compared to their sector so far this year.
Zacks Investment Research Negative
Jan 27, 2025
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