AnaptysBio, Inc.
Description
AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics. Its products include Rosnilimab, an IgG1 antibody that targets PD-1+ T cells, resulting in their agonism or depletion, broadly impacting pathogenic drivers of autoimmune and inflammatory diseases; and ANB032, a non-depleting antibody that binds to the BTLA checkpoint receptor and inhibits activated T cell proliferation; ANB033, a novel anti-CD122 antagonist antibody that targets the shared common beta subunit of the receptors for IL-15 and IL-2; ANB101, a BDCA2 modulator antibody that specifically targets plasmacytoid dendritic cells (pDCs); and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.
About
Earnings
| Date | Estimate EPS | Actual EPS | Difference | % Surprise |
|---|---|---|---|---|
| Nov 3, 2025 | — | — | — | — |
| Aug 4, 2025 | — | — | — | — |
| May 7, 2025 | — | — | — | — |
| Mar 10, 2025 | -1.55 | — | — | — |
| Nov 6, 2024 | -1.65 | -1.14 | 0.51 | -30.91% |
Earnings estimate
|
Next Quarter
(Mar 2025)
|
Next Year
(Dec 2025)
|
|||
|---|---|---|---|---|
| Number of analysts | — | 6 | — | 8 |
| Average estimate | — | -1.52 | — | -5.87 |
| Low estimate | — | -1.77 | — | -7.36 |
| High estimate | — | -1.08 | — | -4.50 |
| Last year EPS | — | -1.64 | — | -6.18 |
Growth estimates
Analyst Ratings
| Date | Firm | Action | Rating | Price Target |
|---|---|---|---|---|
| Feb 4, 2025 |
HC Wainwright & Co.
Emily Bodnar
|
Reiterates | Neutral | Maintains $19 |
| Feb 4, 2025 |
Wolfe Research
Andy Chen
|
Initiates | Outperform | — |
| Dec 19, 2024 |
JP Morgan
Anupam Rama
|
Maintains | Overweight | ▼ Lowers $66 → $36 |
| Dec 18, 2024 |
Truist Securities
John Lee
|
Maintains | Hold | ▼ Lowers $30 → $20 |
| Dec 12, 2024 |
Guggenheim
Yatin Suneja
|
Maintains | Buy | ▼ Lowers $90 → $36 |
| Dec 12, 2024 |
Wells Fargo
Derek Archila
|
Maintains | Overweight | ▼ Lowers $56 → $40 |
| Dec 11, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Downgrade | Neutral | — |
| Dec 2, 2024 |
BTIG
Julian Harrison
|
Downgrade | Neutral | — |
| Nov 12, 2024 |
JP Morgan
Anupam Rama
|
Maintains | Overweight | ▼ Lowers $75 → $66 |
| Nov 6, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Maintains | Buy | ▼ Lowers $55 → $52 |
| Oct 31, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Reiterates | Buy | Maintains $55 |
| Oct 30, 2024 |
UBS
Eliana Merle
|
Maintains | Neutral | ▲ Raises $23 → $33 |
| Oct 21, 2024 |
Guggenheim
Yatin Suneja
|
Maintains | Buy | ▲ Raises $75 → $90 |
| Sep 26, 2024 |
Wedbush
David Nierengarten
|
Reiterates | Outperform | Maintains $42 |
| Aug 15, 2024 |
Truist Securities
John Lee
|
Maintains | Hold | ▲ Raises $20 → $30 |
| Aug 14, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Reiterates | Buy | Maintains $55 |
| Aug 7, 2024 |
JP Morgan
Anupam Rama
|
Maintains | Overweight | ▲ Raises $69 → $75 |
| Aug 6, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Reiterates | Buy | Maintains $55 |
| Jul 22, 2024 |
HC Wainwright & Co.
Emily Bodnar
|
Initiates | Buy | Announces $55 |
| Jul 19, 2024 |
JP Morgan
Anupam Rama
|
Upgrade | Overweight | ▲ Raises $29 → $69 |
| May 10, 2024 |
Wedbush
David Nierengarten
|
Reiterates | Outperform | Maintains $34 |
| Apr 16, 2024 |
Leerink Partners
David Risinger
|
Initiates | Outperform | Announces $47 |
| Apr 11, 2024 |
Wells Fargo
Derek Archila
|
Initiates | Overweight | Announces $56 |
| Apr 1, 2024 |
JP Morgan
Anupam Rama
|
Maintains | Neutral | ▼ Lowers $30 → $28 |
| Mar 12, 2024 |
Wedbush
David Nierengarten
|
Upgrade | Outperform | — |
| Feb 26, 2024 |
BTIG
Julian Harrison
|
Initiates | Buy | Announces $55 |
| Feb 21, 2024 |
Stifel
Alex Schwartz
|
Initiates | Buy | Announces $50 |
| Feb 16, 2024 |
Piper Sandler
Yasmeen Rahimi
|
Initiates | Overweight | Announces $80 |
| Nov 29, 2023 |
Wedbush
David Nierengarten
|
Reiterates | Neutral | Maintains $20 |
| Nov 3, 2023 |
Wedbush
David Nierengarten
|
Maintains | Neutral | ▲ Raises $18 → $20 |
Income statement
| 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|
| Fiscal date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total reported revenue | 17.16M | 10.29M | 63.18M | 75.00M | 8.00M |
| Cost of revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating expense | |||||
| Research & development | 132.28M | 88.80M | 98.50M | 80.03M | 99.34M |
| Selling general and admin | 41.95M | 36.64M | 21.49M | 18.85M | 16.09M |
| Other operating expenses | — | — | — | — | — |
| Operating income | -157.07M | -115.15M | -56.81M | -23.88M | -107.43M |
| Non operating interest income | |||||
| Income | 18.87M | 7.55M | 431,000 | 3.96M | 10.98M |
| Expense | 18.08M | 21.11M | 1.45M | — | 1.04M |
| Other income expense | -7.34M | 12,000 | 37,000 | -11,000 | 1,000 |
| Pretax income | -163.62M | -128.70M | -57.80M | -19.93M | -97.49M |
| Tax provision | -4,000 | 24,000 | — | — | -152,000 |
| Net income | -163.62M | -128.72M | -57.80M | -19.93M | -97.34M |
| Basic EPS | -6.08 | -4.57 | -2.11 | -0.73 | -3.60 |
| Diluted EPS | -6.08 | -4.57 | -2.11 | -0.73 | -3.60 |
| Basic average shares | 26.92M | 28.17M | 27.43M | 27.30M | 27.06M |
| Diluted average shares | 26.92M | 28.17M | 27.43M | 27.30M | 27.06M |
| EBITDA | -135.83M | -105.26M | -54.26M | -18.31M | -95.04M |
| Net income from continuing op. | -163.62M | -128.72M | -57.80M | -19.93M | -97.34M |
| Minority interests | — | — | — | — | — |
| Preferred stock dividends | — | — | — | — | — |
Balance sheet
| 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|
| Fiscal date | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 |
| Total assets | 452.39M | 610.38M | 643.07M | 416.55M | 435.20M |
| Current assets | |||||
| Cash | — | — | — | — | — |
| Cash equivalents | — | — | — | — | — |
| Cash and cash equivalents | 35.97M | 71.31M | 495.73M | 250.46M | 171.02M |
| Other short term investments | 354.94M | 369.93M | 52.37M | 143.20M | 203.21M |
| Accounts receivable | 6.85M | 1.42M | 876,000 | — | — |
| Other receivables | — | — | — | — | — |
| Inventory | — | — | — | — | — |
| Prepaid assets | — | — | 4.90M | 2.91M | 3.51M |
| Restricted cash | — | — | — | — | — |
| Assets held for sale | — | — | — | — | — |
| Hedging assets | — | — | — | — | — |
| Other current assets | 9.08M | 4.55M | 4.90M | 2.91M | 3.51M |
| Non current assets | |||||
| Properties | 22.65M | 23.77M | 25.24M | 5.57M | 4.91M |
| Land and improvements | — | — | — | — | — |
| Machinery furniture equipment | 1.64M | 1.59M | 1.32M | 976,000 | 811,000 |
| Construction in progress | — | — | — | — | — |
| Leases | 203,000 | 203,000 | 203,000 | 527,000 | 575,000 |
| Accumulated depreciation | -6.22M | -5.58M | -4.92M | -4.95M | -4.68M |
| Goodwill | — | — | — | — | — |
| Investment properties | — | — | — | — | — |
| Financial assets | — | — | — | — | — |
| Intangible assets | — | — | — | — | — |
| Investments and advances | 27.03M | 142.94M | 67.10M | 17.55M | 54.31M |
| Other non current assets | 256,000 | 256,000 | 256,000 | 318,000 | 1.54M |
| Total liabilities | 364.29M | 348.28M | 286.64M | 19.82M | 30.19M |
| Current liabilities | |||||
| Accounts payable | 4.70M | 2.78M | 1.74M | 4.22M | 16.24M |
| Accrued expenses | 23.77M | 16.25M | 8.68M | 11.57M | 8.90M |
| Short term debt | 1.78M | 1.64M | 1.51M | 342,000 | 2.25M |
| Deferred revenue | — | — | — | — | — |
| Tax payable | — | — | — | — | — |
| Pensions | 7.20M | 5.38M | 4.18M | 3.69M | 2.15M |
| Other current liabilities | — | — | — | — | 871,000 |
| Non current liabilities | |||||
| Long term debt | 16.04M | 17.81M | 19.45M | — | 654,000 |
| Provision for risks and charges | — | — | — | — | — |
| Deferred liabilities | — | — | — | — | — |
| Derivative product liabilities | — | — | — | — | — |
| Other non current liabilities | 310.81M | 304.41M | 251.09M | — | 654,000 |
| Shareholders equity | |||||
| Common stock | 27,000 | 29,000 | 28,000 | 27,000 | 27,000 |
| Retained earnings | -614.10M | -450.48M | -321.75M | -263.96M | -244.03M |
| Other shareholders equity | -797,000 | -5.25M | -422,000 | -4,000 | 338,000 |
| Total shareholders equity | 88.10M | 262.10M | 356.43M | 396.73M | 405.01M |
| Additional paid in capital | 702.97M | 717.80M | 678.58M | 660.67M | 648.67M |
| Treasury stock | — | — | — | — | — |
| Minority interest | — | — | — | — | — |
Cash flow statement
| 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Activities | |||||||||||
| Net Income | -163.62M | -128.72M | -57.80M | -19.93M | -97.34M | -61.66M | -30.07M | -4.26M | -5.41M | 3.53M | -5.55M |
| Depreciation | 2.38M | 2.34M | 2.09M | 1.62M | 1.41M | 315,000 | 183,000 | 233,000 | 274,000 | 308,000 | 580,000 |
| Deferred Taxes | — | — | — | — | — | — | — | — | — | — | — |
| Stock-Based Compensation | 33.21M | 27.36M | 15.35M | 11.50M | 12.41M | 9.96M | 4.38M | 1.16M | 604,000 | 160,000 | 151,000 |
| Other Non-Cash Items | 18.08M | 21.11M | 1.45M | — | 676,000 | 646,000 | 619,000 | 105,000 | 110,000 | 1.27M | 886,000 |
| Accounts Receivable | -5.43M | -543,000 | -876,000 | — | 174,000 | 1.43M | 3.74M | -4.12M | 229,000 | -1.46M | 268,000 |
| Accounts Payable | 10.94M | 9.70M | -4.74M | -7.69M | 13.20M | 7.08M | 2.22M | 1.25M | 1.95M | 482,000 | -255,000 |
| Other Assets & Liabilities | -1.64M | -1.51M | -72,000 | -1.18M | -999,000 | 139,000 | — | -3.08M | -9.08M | 10.76M | -1.39M |
| Operating Cash Flow | -106.09M | -70.27M | -44.60M | -15.69M | -70.46M | -42.09M | -18.93M | -8.71M | -11.32M | 15.06M | -5.31M |
| Investing Activities | |||||||||||
| Capital Expenditures | -807,000 | -358,000 | -1.35M | -569,000 | -805,000 | -1.06M | -290,000 | -50,000 | -238,000 | -140,000 | -37,000 |
| Net Intangibles | — | — | — | — | — | — | — | — | — | — | — |
| Net Acquisitions | — | — | — | — | — | — | — | — | — | — | — |
| Purchase of Investments | -303.92M | -802.50M | -118.66M | -194.93M | -251.82M | -347.54M | -290.91M | — | — | — | — |
| Sale of Investments | 449.48M | 408.02M | 158.85M | 289.97M | 384.05M | 206.15M | 48.14M | — | — | — | — |
| Investing Cash Flow | 144.75M | -394.85M | 38.84M | 94.48M | 131.43M | -142.45M | -243.06M | -50,000 | -238,000 | -140,000 | -37,000 |
| Financing Activities | |||||||||||
| Long-Term Debt Issuance | — | — | — | — | — | — | — | 10.00M | — | 5.00M | — |
| Long-Term Debt Payments | — | — | — | -1.38M | -7.50M | -6.88M | — | — | — | — | — |
| Other Financing Charges | -11.77M | 32.19M | 249.75M | — | — | -182,000 | -1.60M | -1.40M | -1.45M | -85,000 | — |
| Financing Cash Flow | -59.30M | 44.02M | 252.30M | -2.25M | -11.99M | 213.54M | 290.94M | 8.60M | 39.24M | 4.92M | 1.96M |
| Other Cash Details | |||||||||||
| End Cash Position | 35.97M | 71.31M | 495.73M | 250.52M | 171.08M | 113.66M | 81.25M | 51.29M | 51.74M | 22.19M | 2.81M |
| Income Tax Paid | — | — | — | — | — | — | — | — | — | — | — |
| Interest Paid | — | — | — | 4,000 | 424,000 | 1.04M | 1.09M | 354,000 | 326,000 | 8,000 | — |
| Free Cash Flow | -121.61M | -73.95M | -47.29M | -14.73M | -70.32M | -49.57M | -19.73M | -9.08M | -9.93M | 14.46M | -5.83M |
Article
Article
Article